BrJAC Nº 29 is a special issue dedicated to Omics Tools. It contains an Editorial titled “Proteomics: The Science of Functional and Structural Characterization of Proteins” by Prof. Dr. Mario S. Palma; Interview: “Back to the Future with Proteins and Proteomics” by Prof. Dr. Gilberto B. Domont; Point of View: “Is Proteomics Possible without Mass Spectrometry?” by Prof. Dr. Marcelo V. de Sousa; Letter: “Mass Spectrometry-Based Proteomics to Understand Schizophrenia” by Prof. Dr. Daniel Martins; a Review: “Multi-omics — An Opportunity to Dive into Systems Biology”; and the Articles: “A Contribution to the Analytical Proteomics of Human Intestinal Mucus: Sampling, Sample Preparation, and Protein Identification Strategies”; “In Situ Proteomic Analysis of Glioblastoma Multiforme: A Translational Approach to Improve Prognostic/Diagnostic Routines”.
Proteomics: The Science of Functional and Structural Characterization of Proteins
Mario Sergio Palma
Full Professor of Proteomics
Institute of Biosciences, UNESP
Rio Claro, SP, Brazil
“The Brazilian proteomics community is very active and productive, investigating a wide variety of subjects and reflecting the large biodiversity of Brazilian nature.”
Back to the Future with Proteins and Proteomics
Gilberto B. Domont
Proteomics Unit, IQ- UFRJ
Rio de Janeiro, RJ, Brazil
“My entire scientific life was dedicated to having fun doing research with my students … and helping students to begin and develop their national and international careers.”
Is Proteomics Possible Without Mass Spectrometry?
Marcelo Valle de Sousa
Dept. of Cell Biology, UnB, Brasilia, DF, Brazil
“…materials science must be greatly exploited as a frontier of chemical and analytical chemistry knowledge, but commonly, and as expected, analytical chemists have been the protagonists.”
Mass Spectrometry-Based Proteomics to Understand Schizophrenia
Daniel Martins de Souza
Associate Professor of Biochemistry
Institute of Biology, Unicamp
Campinas, SP, Brazil
“Proteomics emerged in the post genomic era as an alternative toolbox ... In the case of schizophrenia, we can easily see that proteomics has opened roads that...”
Review: Multi-Omics: An Opportunity to Dive into Systems Biology
Emerson A. F. dos Santos, Elisa C. S. Cruz, Henrique C. Ribeiro, Luidy D. Barbosa, Flávia S. Zandonadi, Alessandra Sussulini
This review describes a workflow example regarding multi-omics data integration, indicating mathematical and computational tools in analysis pipelines that use various methods to perform a sequence of tasks, which would be able to describe biological processes within the systems biology context.
A Contribution to the Analytical Proteomics of Human Intestinal Mucus: Sampling, Sample Preparation, and Protein Identification Strategies
Paola A. G. Buitrago, Carlos A. G. Correa, Mario S. Osorio, Gonzalo T. Ocampo, Hector Henrique F. Koolen, Marco A Z. Arruda
Several analytical proteomics strategies are presented in this study, which contribute to the proteomic map of human intestinal mucus, enlarging knowledge of this important sample.
In Situ Proteomic Analysis of Glioblastoma Multiforme: A Translational Approach to Improve Prognostic/Diagnostic Routines
Anally R. S. Menegasso, Marcel Pratavieira, Lucilene D. dos Santos, Flávio O. Lima, Marcelo P. T. Moraes, Marco Antonio Zanini, Mario Sergio Palma
In order to evaluate the application of MALDI MSI to the study of Glioblastoma, some sections of formalin fixed paraffin embedded samples of GBM were submitted to classical immunohistochemistry, for defining the profile of molecular markers of GBM grade IV.
COVID-19: How the Oswaldo Cruz Foundation is Working to Address the Pandemic in Brazil
The ‘Observatory COVID-19’ was created by Fiocruz with the aim of integrating analyses, technologies, proposals and solutions to face the COVID-19 pandemic.
Real-Time Search Enables a New Gold Standard for TMT Quantitation Accuracy on the Orbitrap Eclipse Tribrid Mass Spectrometer
The utility of Real-Time Search for TMT SPS MS3-based quantitation, which allows for intelligent acquisition methods that improve quantitation accuracy, precision, and proteome coverage was evaluated.
Orbitrap Eclipse™ Tribrid™ Mass Spectrometer — Obtain high confidence insights for very complex molecules
Address complex challenges more effectively with the latest improvements in calibration, ion transmission efficiency, mass range, data acquisition speed and much more!
Pittcon - The World’s Leading Conference and Expo on Laboratory Science
Don’t Miss Pittcon 2021 on March 6 – 10 at the Ernest N. Morial Convention Center, New Orleans, LA USA.
SelectScience® – The Scientists’ Channel
SelectScience® promotes scientists and their work, accelerating the communication of successful science.
CHROMacademy – the world’s largest eLearning website for analytical scientists
CHROMacademy helps increase your knowledge, efficiency and productivity in the lab.